Endocrine Abstracts

Unsuspected adrenal masses, or incidentalomas, are increasingly found with the widespread use of thoracic and abdominal imaging. These masses may be hormonally active or nonfunctional and benign or malignant. Clinicians must determine the nature of the mass to decide what treatment, if any, is needed.In our 17 year experience, we observed 232 patients (158 females, 74 males aged 22-91, mean age 69) affected with monolateral incidentaloma. 58 of them (25%...

Langerhans cell histiocytosis (LCH) is a rare entity characterized by clonal proliferation and accumulation of cells resembling the epidermal dendritic cells called Langerhans cells (distinct margins, pink granular cytoplasm, Birbeck granules at electron microscopy and CD1 positivity by immunocytochemistry). These cells in combination with lymphocytes, eosinophils ad normal hystiocytes form the typical LCH lesions. About half of affected patients have extraskeletal manifestati...

Autoimmune thyroiditis (AT) may occur as a single disease or associated with further endocrine and non endocrine autoimmune diseases (NEAD). Chronic autoimmune gastritis (CAG) is the more frequently associated NEAD. A prevalent Th1-representative pattern of cytokines and chemokines has been described in isolated autoimmune thyroiditis. However, the behaviour of chemokines when AT is associated with CAG is not known. Aim of the study has been to measure serum levels of CXCL10 i...

Introduction: Metoclopramide is known to exert stimulatory effects on catecholamine secretion, having been used in the past as provocative test in the diagnosis of pheochromocytoma. We describe a patient with an incidentally discovered pheochromocytoma after metoclopramide administration.Case report: A 64 years-old woman underwent total thyroidectomy for multinodular goiter with ‘follicular proliferation Thy 3’ at FNAB of the target nodule. The...